Τίτλος:
Spleen Size Changes in Children with Homozygous β‐Thalassaemia in Relation to Blood Transfusion
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
18 thalassaemic children, aged 3.5 to 13 years comprise our clinical material. In 14 of them, clinically elicited spleen markings, haematocrit, blood platelet count and red cell morphology were studied daily for a whole period between 2 transfusions. In 10 patients considerable changes in spleen size were noticed. According to our clinical observations the spleen size starts decreasing 1 to 3 d after blood transfusion up to the 10th posttransfusion day fluctuating thereafter to reach its maximum size again prior to the next blood transfusion. The decrease of spleen size was followed by an increase of haematocrit and blood platelet count and vice versa. 4 additional children were studied clinically only twice: prior to and 7 to 10 d after blood transfusion. A definite decrease of the spleen size following blood transfusion was observed. Spleen and liver 99mTc‐sulfur colloid uptake was studied in 10 of the above children prior to and 7 to 10 d after blood transfusion. Statistically significant post‐transfusion increase of the spleen uptake was demonstrated. Our findings suggest that (a) splenic size is relevant to blood volume sequestrated int this organ, (b) splenic radioactive uptake increases with its post‐transfusion reduction in size. © Munksgaard 1982
Συγγραφείς:
Karpathios, Th.
Antypas, A.
Dimitriou, P.
Nicolaidou, P.
Fretzayas, A.
Thomaidis, Th.
Matsaniotis, N.
Περιοδικό:
Scandinavian Journal of Haematology
Λέξεις-κλειδιά:
beta thalassemia; blood and hemopoietic system; blood transfusion; human cell; major clinical study; phagocytosis; reticuloendothelial system; spleen; theoretical study, Adolescent; Blood Transfusion; Child; Child, Preschool; Female; Hematocrit; Homozygote; Humans; Liver; Male; Organ Size; Platelet Count; Spleen; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid; Thalassemia
DOI:
10.1111/j.1600-0609.1982.tb00518.x
