Περίληψη:
Irritable Bowel Syndrome (IBS) represents a functional disorder of
gastrointestinal tract without the presence of an anatomic defect, in
which abdominal pain is relieved with defecation and is associated with
altered bowel habits. IBS includes a wide range of symptoms while its
pathophysiology is very complicated. Recent studies indicate that the
most important mechanisms include visceral sensitivity, abnormal gut
motility and autonomous nervous system dysfunction. The interactions
between these three mechanisms make bowel’s function susceptible to many
exogenous and endogenous factors like gastrointestinal flora, feeding
and psychosocial factors. Recent data indicate that according to the
above mechanisms, the influence of genetic factors and polymorphisms of
human DNA in the development of IBS is equally important.
Συγγραφείς:
Karantanos, Theodoros
Markoutsaki, Theofano
Gazouli, Maria and
Anagnou, Nicholas P.
Karamanolis, Dimitrios G.
