The effect of functional endoscopic sinus surgery on patients with asthma and CRS with nasal polyps

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3146984 17 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
The effect of functional endoscopic sinus surgery on patients with
asthma and CRS with nasal polyps
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Aim: To study the effect of functional endoscopic sinus surgery (FESS)
in patients with chronic rhinosinusitis (CRS) and nasal polyps (NP) with
concomitant asthma.
Design: The study was designed to evaluate prospectively whether FESS
can influence parameters of asthma in patients with CRS with nasal
polyps.
Methods and Results: One hundred thirty seven patients were recruited
from the ENT-Allergy and Panedoscopy Clinic of the ENT Department. All
selected patients underwent medical therapy for CRS and NP for 12 weeks,
and in case of no improvement, they proceeded to surgical treatment.
They also underwent pre- and post-treatment subjective and objective
measurements for CRS and asthma. In the study, 86 patients were finally
evaluated who completed the protocol and were followed up for a period
of 12 months.
The patients showed statistically significant improvement of the
objective measurements for asthma, from baseline to six and twelve
months follow-up. No significant increase was found in the proportion of
patients with well or very well overall asthma-control during the
follow-up period. There was a clear improvement in the use of
bronchodilators, oral steroids and need for hospitalization for asthma.
Conclusions: Obviously, there is a link between CRS with NP and asthma.
The data analysis of our study supports the hypothesis that FESS could
have beneficial effect on both diseases improving objective and
subjective measurements.
Έτος δημοσίευσης:
2010
Συγγραφείς:
Proimos, E.
Papadakis, C. E.
Chimona, T. S.
Kiagiadaki, D.
and Ferekidis, E.
Yiotakis, J.
Περιοδικό:
Rhinology
Εκδότης:
INT RHINOLOGIC SOC
Τόμος:
48
Αριθμός / τεύχος:
3
Σελίδες:
331-338
Λέξεις-κλειδιά:
endoscopic sinus surgery; chronic rhinosinusitis with nasal polyps;
asthma
Επίσημο URL (Εκδότης):
DOI:
10.4193/Rhin09.123
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.