Τίτλος:
Validation of the Finnish diabetes risk score (FINDRISC) questionnaire
for screening for undiagnosed type 2 diabetes, dysglycaemia and the
metabolic syndrome in Greece
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Aim. - The present study aimed to validate the Finnish Type 2 Diabetes
Risk Score (FINDRISC) questionnaire for its ability to predict the
presence of any glucose homoeostasis abnormalities and the metabolic
syndrome (MetS) in the Greek population.
Methods. - Validation was performed on a sample of individuals who had
agreed to participate in a screening program for type 2 diabetes (T2D)
prevention (the Greek part of the DE PLAN study), using both FINDRISC
and oral glucose tolerance tests (OGTT). Impaired fasting glucose (IFG)
was defined as a fasting plasma glucose level of 6.1-6.9 mmol/L, and
impaired glucose tolerance (IGT) as a 2-h plasma glucose of 7.8-11.0
mmol/L. The predictive value of the FINDRISC was cross-sectionally
evaluated using the area under the receiver operating characteristic
(AUROC) curve method.
Results. - A total of 869 individuals (379 men, aged 56.2 +/- 10.8
years) were screened from the general population living in the city and
suburbs of Athens. OGTT revealed the presence of unknown diabetes in 94
cases (10.8%), IFG in 85 (9.8%) and IGT in 109(12.6%). The
sensitivity of a FINDRISC score greater or equal to 15 (45% of the
population) to predict unknown diabetes was 81.9% and its specificity
was 59.7%. The AUROC curve for detecting unknown diabetes was 0.724
(95% CI: 0.677-0.770). For any dysglycaemia, the AUROC curve was 0.716
(0.680-0.752) while, for detection of the MetS, it was 0.733
(0.699-0.767).
Conclusion. The FINDRISC questionnaire performed well as a screening
tool for the cross-sectional detection of unknown diabetes, IFG, IGT and
the MetS in the Greek population. (C) 2010 Elsevier Masson SAS. All
rights reserved.
Συγγραφείς:
Makrilakis, K.
Liatis, S.
Grammatikou, S.
Perrea, D. and
Stathi, C.
Tsiligros, P.
Katsilambros, N.
Περιοδικό:
Diabetes & Metabolism
Λέξεις-κλειδιά:
Diabetes screening; FINDRISC questionnaire; Diabetes prevention;
Diagnosis; Type 2 diabetes; Impaired fasting glucose; Impaired glucose
tolerance; Greece
DOI:
10.1016/j.diabet.2010.09.006
