Τίτλος:
RANIBIZUMAB FOR THE TREATMENT OF EXUDATIVE AGE-RELATED MACULAR
DEGENERATION ASSOCIATED WITH RETINAL PIGMENT EPITHELIAL TEAR
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: To evaluate the efficacy of intravitreal ranibizumab in eyes
with exudative age-related macular degeneration associated with retinal
pigment epithelial tear.
Methods: In this retrospective case series, patients with active
exudative age-related macular degeneration associated with retinal
pigment epithelial tear were treated by repeated injections of
intravitreal ranibizumab. The outcome measures were best-corrected
visual acuity and the signs of lesion activity, as evaluated by optical
coherence tomography, fluorescein angiography, and indocyanine green
angiography.
Results: Twenty-one eyes of 20 patients were followed-up for a median of
12 months (range, 6-28 months). The median number of injections was 7
(range, 3-15). The best-corrected visual acuity improved in 6 eyes
(28.57%), remained stable in 12 (57.14%), and decreased in 3
(14.28%). At the end of the follow-up time, 19 eyes (90.47%) had an
inactive neovascular lesion in angiography, while 18 eyes (85.71%) had
no signs of intraretinal or subretinal fluid.
Conclusion: Intravitreal ranibizumab was effective in improving or
stabilizing vision and resulting in a quiescent lesion in the majority
of patients with exudative age-related macular degeneration associated
with retinal pigment epithelial tear. The functional results were
apparently better in eyes without foveal involvement by the retinal
pigment epithelial tear. RETINA 31:1083-1088, 2011
Συγγραφείς:
Rouvas, Alexandros A.
Ladas, Ioannis D.
Georgalas, Ilias and
Vergados, Ioannis
Papakonstantinou, Dimitrios
Kotsolis,
Athanasios I.
Περιοδικό:
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Εκδότης:
Lippincott, Williams & Wilkins
Λέξεις-κλειδιά:
exudative age-related macular degeneration; ranibizumab; retinal pigment
epithelial tear
DOI:
10.1097/IAE.0b013e318207d1a3
