Τίτλος:
Infants with viral bronchiolitis demonstrate two distinct patterns of
nocturnal oxyhaemoglobin desaturation
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
AimThis study aimed to demonstrate that viral bronchiolitis is
associated with intermittent oxygen saturation of haemoglobin (SpO(2))
drops (3%) and low basal SpO(2) between episodes of haemoglobin
desaturation.
MethodsInfants with bronchiolitis underwent pulse oximetry during the
first night following hospital admission and a subgroup of them
underwent repeat oximetry before hospital discharge. Oximetry was also
performed in infants with partial upper airway obstruction (UAO) and
without lung disease and in control participants without UAO or lung
disease.
ResultsWe enrolled 53 infants: 21 with bronchiolitis, 11 with UAO and 21
healthy controls. Participants with bronchiolitis had lower basal SpO(2)
(median 93.7% [10th-90th percentiles: 91.1-96.8]) than the subjects
with UAO (96.9% [95.3-98.1]; p<0.01) or the controls (98.7%
[96.9-99.3]; p<0.01). The bronchiolitis group was not different from
the UAO group regarding the desaturation index (23.3 episodes/hour
[10.3-46.6] and 15.5 episodes/hour [5.4-36.4], respectively;
p=0.08), but differed significantly from the controls (3.1 episodes/hour
[0.3-5.5]; p<0.01). The basal SpO(2) and desaturation index improved
in 10 subjects with bronchiolitis who had follow-up oximetry before
discharge, but these indices remained abnormal when compared to values
in the control group.
ConclusionBronchiolitis was characterised by low nocturnal basal SpO(2)
and intermittent SpO(2) drops.
Συγγραφείς:
Kaditis, Athanasios G.
Katsouli, Georgia
Malakasioti, Georgia
and Kaffe, Katerina
Gemou-Engesaeth, Vasiliki
Alexopoulos,
Emmanouel I.
Περιοδικό:
ACTA PAEDIATRICA SCANDINAVICA
Λέξεις-κλειδιά:
bronchiolitis; infancy; nocturnal hypoxaemia; oximetry; sleep-disordered
breathing
