Περίληψη:
The recent coronavirus outbreak has spread worldwide, with the exception
of Antarctica, causing serious social and economic disruption. All
disciplines of the science community are driven to confront the impact
of the COVID-19 pandemic, as currently, there is neither prophylactic
nor therapeutic treatments available. Due to the urgency of the
situation, various research strategies are ongoing, in order to evaluate
the therapeutic efficacy of repurposed and experimental drugs. The
present review presents the most promising repurposed regimens, which
may be used for the treatment of COVID-19. The drugs/bioactive
substances presented herein belong to diverse therapeutic classes,
including antimalarial, cardioprotective, angiotensin-converting enzyme
2 inhibitors, antiviral, anti-inflammatory and antiparasitic drugs.
Therapeutic perspectives of vaccination and passive immunization are
also reviewed.
