Τίτλος:
Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups. © 2005 American Chemical Society.
Συγγραφείς:
Barbayianni, E.
Fotakopoulou, I.
Schmidt, M.
Constantinou-Kokotou, V.
Bornscheuer, U.T.
Kokotos, G.
Περιοδικό:
The Journal of Organic Chemistry
Λέξεις-κλειδιά:
Bacteria; Benzene; Carboxylation; Esterification, Bacillus subtilis (BS2); Functional groups; Moieties; Selective removal, Enzymes, amino acid; bacterial enzyme; benzyl derivative; carboxylic acid; ester; esterase; fungal enzyme; methyl group; peptide; phospholipase A2 inhibitor; recombinant enzyme; triacylglycerol lipase, article; Bacillus subtilis; Candida antarctica; carbon nuclear magnetic resonance; chemical reaction; chemical structure; enzyme activity; enzyme inhibition; Escherichia coli; hydrolysis; nonhuman; proton nuclear magnetic resonance, Bacillus subtilis; Benzene; Candida; Esters; Hydrolysis; Lipase; Methylation; Molecular Structure; Pancreatic Elastase; Peptides; Phospholipases A
